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L-Arginine Supplements Nitric Oxide Scientific Studies

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The metabolism of L-arginine leads to the formation of nitric oxide an important catalyst for healthy dilation of blood vessels, circulation, and blood flow. In a prospective, double-blind trial, L-arginine supplementation supported healthy endothelial function- in blood vessels of male volunteers (1)

Food Sources. Dietary arginine is found in chocolate, wheat germ and flour, buckwheat, granola, oatmeal, dairy products (cottage cheese, ricotta, nonfat dry milk, skim yogurt), beef (roasts, steaks), pork (Canadian bacon, ham), nuts (coconut, pecans, cashews, walnuts, almonds, Brazil nuts, hazel nuts, peanuts), seeds (pumpkin, sesame, sunflower), poultry (chicken and turkey light meat), wild game (pheasant, quail), seafood (halibut, lobster, salmon, shrimp, snails, tuna in water), chick peas, and cooked soybeans. (2)

In other studies, L-arginine promoted healthy platelet function and enhanced exercise tolerance. Additional trials indicate that L-arginine may support healthy lipid metabolism enhancing its cardiovascular support properties. Arginine has demonstrated immune-stimulatory activity and may promote the utilization of nitric acid by scavenger cells for defense mechanisms. Enhancement of immune messenger compounds has also been observed in several studies with L-arginine.(3)

In a study involving elderly individuals, L-arginine accelerated tissue repair, and supported immune health. (3) In men with low urinary nitric oxide values, I-arginine may support healthy sexual function. Some but not all research involving I-arginine supplementation for sperms motility have produced positive results. Arginine plays a role in the syntheses of hormones such as insulin and growth hormone and has demonstrated the potential to support glucose metabolism and growth hormone production in pigs. (5)

Nitric oxide is also a mediator of neurotransmission in the brain, supporting memory under the circumstances of reduced intracellular arginine. Preliminary studies suggest that L-arginine may support bladder comfort and function in some individuals. I-Arginine is a safe, versatile amino acid precursor of nitric oxide associated with promoting cardiovascular health, immune support, sexual function, and memory. (6)

References:
(1) http://ajrccm.atsjournals.org/cgi/content/abstract/163/4/887
(2)Murray, N.D., Michael T. and Pizzorno, N.D., Joseph, Encyclopedia of Natural Medicine (Rocklin, California: 1991, Prima Publishing), page 359. ISBN 0-55958-091-7
(3) http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&list_uids=7877530&dopt=citation
(4) http://circ.ahajournals.org/cgi/content/full/105/18/2133
(5) http://jn.nutrition.org/cgi/content/abstract/134/3/625
(6) http://jn.nutrition.org/cgi/content/abstract/135/2/212